{"id":44349,"date":"2026-08-04T16:05:15","date_gmt":"2026-08-04T12:05:15","guid":{"rendered":"https:\/\/dnagtx.com\/?p=44349"},"modified":"2026-09-25T12:32:42","modified_gmt":"2026-09-25T08:32:42","slug":"dr-leonardo-varuzza","status":"publish","type":"post","link":"https:\/\/dnagtx.com\/portuguese\/dr-leonardo-varuzza\/","title":{"rendered":"Dr. Leonardo Varuzza"},"content":{"rendered":"<div data-elementor-type=\"wp-post\" data-elementor-id=\"44349\" class=\"elementor elementor-44349\" data-elementor-post-type=\"post\">\n\t\t\t\t<div class=\"has_eae_slider elementor-element elementor-element-ce77f8b e-flex e-con-boxed e-con e-parent\" data-eae-slider=\"99192\" data-id=\"ce77f8b\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"has_eae_slider elementor-element elementor-element-bd60dc9 e-con-full e-flex e-con e-child\" data-eae-slider=\"61566\" data-id=\"bd60dc9\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4f0b7e9 elementor-widget elementor-widget-image\" data-id=\"4f0b7e9\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"799\" height=\"799\" src=\"https:\/\/dnagtx.com\/wp-content\/uploads\/2026\/02\/Dr.-Leonardo-Varuzza.webp\" class=\"attachment-full size-full wp-image-41190\" alt=\"\" srcset=\"https:\/\/dnagtx.com\/wp-content\/uploads\/2026\/02\/Dr.-Leonardo-Varuzza.webp 799w, https:\/\/dnagtx.com\/wp-content\/uploads\/2026\/02\/Dr.-Leonardo-Varuzza-300x300.webp 300w, https:\/\/dnagtx.com\/wp-content\/uploads\/2026\/02\/Dr.-Leonardo-Varuzza-150x150.webp?crop=1 150w, https:\/\/dnagtx.com\/wp-content\/uploads\/2026\/02\/Dr.-Leonardo-Varuzza-768x768.webp 768w\" sizes=\"(max-width: 799px) 100vw, 799px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c8148da elementor-widget elementor-widget-heading\" data-id=\"c8148da\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Dr. Leonardo Varuzza<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7ce86df elementor-widget elementor-widget-heading\" data-id=\"7ce86df\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Diretor de Bioinform\u00e1tica<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-aeb7f65 elementor-align-center elementor-icon-list--layout-traditional elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list\" data-id=\"aeb7f65\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon-list.default\">\n\t\t\t\t\t\t\t<ul class=\"elementor-icon-list-items\">\n\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.linkedin.com\/in\/leonardovaruzza?utm_source=share&#038;utm_campaign=share_via&#038;utm_content=profile&#038;utm_medium=android_app\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fab-linkedin\" viewbox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 32H31.9C14.3 32 0 46.5 0 64.3v383.4C0 465.5 14.3 480 31.9 480H416c17.6 0 32-14.5 32-32.3V64.3c0-17.8-14.4-32.3-32-32.3zM135.4 416H69V202.2h66.5V416zm-33.2-243c-21.3 0-38.5-17.3-38.5-38.5S80.9 96 102.2 96c21.2 0 38.5 17.3 38.5 38.5 0 21.3-17.2 38.5-38.5 38.5zm282.1 243h-66.4V312c0-24.8-.5-56.7-34.5-56.7-34.6 0-39.9 27-39.9 54.9V416h-66.4V202.2h63.7v29.2h.9c8.9-16.8 30.6-34.5 62.9-34.5 67.2 0 79.7 44.3 79.7 101.9V416z\"><\/path><\/svg>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">LinkedIn Profile<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t<\/ul>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-05400cb elementor-widget elementor-widget-n-accordion\" data-id=\"05400cb\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;default_state&quot;:&quot;all_collapsed&quot;,&quot;max_items_expended&quot;:&quot;one&quot;,&quot;n_accordion_animation_duration&quot;:{&quot;unit&quot;:&quot;ms&quot;,&quot;size&quot;:400,&quot;sizes&quot;:[]}}\" data-widget_type=\"nested-accordion.default\">\n\t\t\t\t\t\t\t<div class=\"e-n-accordion\" aria-label=\"Accordion. Open links with Enter or Space, close with Escape, and navigate with Arrow Keys\">\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-5500\" class=\"e-n-accordion-item\" >\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"1\" tabindex=\"0\" aria-expanded=\"false\" aria-controls=\"e-n-accordion-item-5500\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><div class=\"e-n-accordion-item-title-text\"> Ver Perfil <\/div><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><i aria-hidden=\"true\" class=\"icon icon-up-arrow1\"><\/i><\/span>\n\t\t\t<span class='e-closed'><i aria-hidden=\"true\" class=\"icon icon-down-arrow1\"><\/i><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div class=\"has_eae_slider elementor-element elementor-element-5df673f e-con-full e-flex e-con e-child\" data-eae-slider=\"38276\" role=\"region\" aria-labelledby=\"e-n-accordion-item-5500\" data-id=\"5df673f\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-9290525 elementor-widget__width-initial elementor-widget elementor-widget-heading\" data-id=\"9290525\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Dr. Varuzza is the Director of Bioinformatics at DNA GTx, who brings deep, hands-on expertise in large-scale sequencing and data analysis to bioinformatics operations. Drawing on extensive experience, he ensures bioinformatics pipelines are scalable, accurate, and seamlessly integrated into real-world workflows.<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-5501\" class=\"e-n-accordion-item\" >\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"2\" tabindex=\"-1\" aria-expanded=\"false\" aria-controls=\"e-n-accordion-item-5501\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><div class=\"e-n-accordion-item-title-text\"> Publications <\/div><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><i aria-hidden=\"true\" class=\"icon icon-up-arrow1\"><\/i><\/span>\n\t\t\t<span class='e-closed'><i aria-hidden=\"true\" class=\"icon icon-down-arrow1\"><\/i><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div class=\"has_eae_slider elementor-element elementor-element-3b1ddbb e-flex e-con-boxed e-con e-child\" data-eae-slider=\"29013\" role=\"region\" aria-labelledby=\"e-n-accordion-item-5501\" data-id=\"3b1ddbb\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-517c26a elementor-widget elementor-widget-text-editor\" data-id=\"517c26a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<ol><li>MAKI, KATHERINE A.; WOLFF, BRIAN; Varuzza, Leonardo; GREEN, STEFAN J.; BARB, JENNIFER J.2023.<\/li><\/ol><p>Multi-amplicon microbiome data analysis pipelines for mixed orientation sequences using QIIME2: Assessing reference database, variable region and pre-processing bias in classification of mock bacterial community samples In PLoS One, v.18, p.e0280293\u00a0<a href=\"https:\/\/journals.plos.org\/plosone\/article?id=10.1371\/journal.pone.0280293\">Publication Link<\/a><\/p><ol start=\"2\"><li>DEZAN, MARCIA R.; RIBEIRO, INGRID HELENA; OLIVEIRA, VAL\u00c9RIA B.; VIEIRA, JULIANA B.; GOMES, FRANCISCO C.; FRANCO, LUCAS A.M.; Varuzza, Leonardo; RIBEIRO, ROBERTO; CHINOCA, KAREN ZIZA; LEVI, JOS\u00c9 EDUARDO; KRIEGER, JOS\u00c9 EDUARDO; PEREIRA, ALEXANDRE COSTA; GUALANDRO, SANDRA F.M.; ROCHA, VANDERSON G.; MENDRONE-JUNIOR, ALFREDO; SABINO, ESTER CERDEIRA; DINARDO, CARLA LUANA.<\/li><\/ol><p>RHD and RHCE genotyping by next-generation sequencing is an effective strategy to identify molecular variants within sickle cell disease patients In Blood Cells, Molecules &amp; Diseases (Print), v.1, p.S10799796173004\u00a0<a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S1079979617300499?via%3Dihub\">Publication Link<\/a><\/p><ol start=\"3\"><li>NISHIBE, C.; CANEVARI CASTELAO, A. B.; DALLA COSTA, R.; PINTO, B. J.; VARUZZA, L.; CATALDI, A. A.; BERNARDELLI, A.; BIGI, F.; BLANCO, F. C.; ZUMARRAGA, M. J.; ALMEIDA, N. F.; ARAUJO, F. R.<\/li><\/ol><p>. Draft Genome Sequence of Mycobacterium bovis 04-303, a Highly Virulent Strain from Argentina In Genome Announcements, v.1, p.e00931-13 &#8211; e00931-13\u00a0<a href=\"https:\/\/journals.asm.org\/doi\/10.1128\/genomea.00931-13\">Publication Link<\/a><\/p><ol start=\"4\"><li>Ramos, Rommel Thiago Juc\u00e1; Carneiro, Adriana Ribeiro; de Castro Soares, Siomar; Barbosa, Silvanira; VARUZZA, L.; ORABONA, GUILHERME; Tauch, Andreas; Azevedo, Vasco; Schneider, Maria Paula; SILVA, A.<\/li><\/ol><p>High efficiency application of a mate-paired library from Next-Generation Sequencing to PostLight sequencing: Corynebacterium pseudotuberculosis as a case study for microbial de novo genome assembly In Journal of Microbiological Methods, v.95, p.441 \u2013 447.\u00a0<a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0167701213001814?via%3Dihub\">Publication Link<\/a><\/p><ol start=\"5\"><li>Novaes, Jeniffer; RANGEL, L. T. L. D.; FERRO, M.; Abe, Ricardo Y.; Manha, Alessandra P.S.; de Mello, Joana C.M.; VARUZZA, L.; Durham, Alan M.; Madeira, Alda Maria B.N.; Gruber, Arthur. 2012.<\/li><\/ol><p>A comparative transcriptome analysis reveals expression profiles conserved across three Eimeria spp. of domestic fowl and associated with multiple developmental stages In International Journal for Parasitology, v.42, p.39 \u2013 48.\u00a0<a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S002075191100275X?via%3Dihub\">Publication Link<\/a><\/p><ol start=\"6\"><li>VARUZZA, L.; Carlos A de B. Pereira. 2010.<\/li><\/ol><p>Significance test for comparing digital gene expression profiles: Partial likelihood application In Chilean Journal of Statistics, v.1, p.91 \u2013 102.\u00a0<a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S002075191100275X?via%3Dihub\">Publication Link<\/a><\/p><ol start=\"7\"><li>Ribeiro-dos-Santos, \u00c2ndrea; Khayat, Andr\u00e9 S.; Silva, Artur; Alencar, Dayse O.; Lobato, Jess\u00e9; Luz, Larissa; Pinheiro, Daniel G.; VARUZZA, L.; Assump\u00e7\u00e3o, Monica; Assump\u00e7\u00e3o, Paulo; Santos, Sidney; Zanette, Dalila L.; Silva, Wilson A.; Burbano, Rommel; Darnet, Sylvain. 2010.<\/li><\/ol><p>Ultra-Deep Sequencing Reveals the microRNA Expression Pattern of the Human Stomach In Plos One, v.5, p.e13205.\u00a0<a href=\"https:\/\/journals.plos.org\/plosone\/article?id=10.1371\/journal.pone.0013205\">Publication Link<\/a><\/p><ol start=\"8\"><li>Silveira, Nelson JF; VARUZZA, L.; Machado-Lima, Ariane; Lauretto, Marcelo S; Pinheiro, Daniel G; Rodrigues, Rodrigo V; Severino, Patricia; Nobrega, Francisco G; Gencapo, Head and Neck Genome Project; Silva Jr, WA; de B Pereira, Carlos A; Tajara, Eloiza H. 2008.<\/li><\/ol><p>Searching for molecular markers in head and neck squamous cell carcinomas (HNSCC) by statistical and bioinformatic analysis of larynx-derived SAGE libraries In BMC Medical Genomics, v.1, p.56.\u00a0<a href=\"https:\/\/link.springer.com\/article\/10.1186\/1755-8794-1-56\">Publication Link<\/a><\/p><ol start=\"9\"><li>Ricardo Z. N. V\u00eancio; VARUZZA, L.; Carlos A de B. Pereira; Helena Paula Brentani; Ilya Shmulevich. 2007.<\/li><\/ol><p>Simcluster: clustering enumeration gene expression data on the simplex space In BMC Bioinformatics, v.8, p.246.\u00a0<a href=\"https:\/\/link.springer.com\/article\/10.1186\/1471-2105-8-246\">Publication Link<\/a><\/p><ol start=\"10\"><li>DURHAM, A. M.; KASHIWABARA, A. Y.; Matsunaga, T. G.; Ahagon, P. H.; Rainone, F.; VARUZZA, L.; GRUBER, A. 2005.<\/li><\/ol><p>EGene: a configurable pipeline generation system for automated sequence analysis. In Bioinformatics (Oxford), v.21, p.2812 \u2013 2813.\u00a0<a href=\"https:\/\/academic.oup.com\/bioinformatics\/article-lookup\/doi\/10.1093\/bioinformatics\/bti424\">Publication Link<\/a><\/p><ol start=\"11\"><li>BRUNSTEIN, A.; VARUZZA, L.; Gerdine, F. O.; Briones, M. R.\u00a0S. 2004.<\/li><\/ol><p>Changes in G+C content of a neutrally evolving gene under a non-reversible dynamics measured by computer simulations based on experimental evolution data In Genetics and Molecular Biology, v.27, p.632 \u2013 636.\u00a0<a href=\"https:\/\/academic.oup.com\/bioinformatics\/article-lookup\/doi\/10.1093\/bioinformatics\/bti424\">Publication Link<\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>Dr. Leonardo Varuzza Director of Bioinformatics LinkedIn Profile View Profile Dr. Varuzza is the Director of Bioinformatics at DNA GTx, who brings deep, hands-on expertise in large-scale sequencing and data analysis to bioinformatics operations. Drawing on extensive experience, he ensures bioinformatics pipelines are scalable, accurate, and seamlessly integrated into real-world workflows. Publications MAKI, KATHERINE A.; [&hellip;]<\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_wpcom_ai_launchpad_first_post":false,"footnotes":"","jetpack_post_was_ever_published":true},"categories":[119],"tags":[120],"class_list":["post-44349","post","type-post","status-publish","format-standard","hentry","category-professional-profile","tag-professional-profile"],"jetpack_shortlink":"https:\/\/wp.me\/pfZTez-bxj","jetpack_featured_media_url":"","_links":{"self":[{"href":"https:\/\/dnagtx.com\/portuguese\/wp-json\/wp\/v2\/posts\/44349","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dnagtx.com\/portuguese\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dnagtx.com\/portuguese\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dnagtx.com\/portuguese\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/dnagtx.com\/portuguese\/wp-json\/wp\/v2\/comments?post=44349"}],"version-history":[{"count":16,"href":"https:\/\/dnagtx.com\/portuguese\/wp-json\/wp\/v2\/posts\/44349\/revisions"}],"predecessor-version":[{"id":45124,"href":"https:\/\/dnagtx.com\/portuguese\/wp-json\/wp\/v2\/posts\/44349\/revisions\/45124"}],"wp:attachment":[{"href":"https:\/\/dnagtx.com\/portuguese\/wp-json\/wp\/v2\/media?parent=44349"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dnagtx.com\/portuguese\/wp-json\/wp\/v2\/categories?post=44349"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dnagtx.com\/portuguese\/wp-json\/wp\/v2\/tags?post=44349"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}