Focused Mutation Profiling for Solid Tumors
Detecting Key Mutations to Personalize Cancer Care
DNA GTx’s Hotspot Panel offers high-sensitivity profiling of critical hotspot regions across 60 oncogenes and tumor suppressor genes, using formalin-fixed, paraffin-embedded (FFPE) tissue samples.
Who is this Test for?
- Patients with a confirmed diagnosis
- Individuals being considered for targeted therapy or clinical trials
- Cases where tumor profiling can inform prognosis or risk stratification
Variant Types Detected
Single Nucleotide Variants (SNVs)
- SNVs are single base changes between reference and the patient's genome.
Insertions and Deletions (Indels)
Insertion
Deletion
- Indels are small changes in DNA where a few bases are either added (insertion) or removed (deletion).
Some Copy Number Variants (CNVs)
Amplification / Duplication
Deletion
- Parts of DNA that are copied too many times or missing. This can make cancer genes overactive or silence protective genes.
Some Gene Fusions / Rearrangements
- When two different genes break and join together, forming a “hybrid gene.” This new gene can send the wrong signals that drive cancer growth.
What it Screens for
- Mutations in 60 key genes linked to
- Lung cancer
- Colorectal cancer
- Breast cancer
- Pancreatic cancer
- Melanoma
- Other solid tumors
Show list
- Liver cancer
- Ovarian cancer
- Prostate cancer
- Bladder cancer
- Gastric cancer
- Endometrial cancer
- Renal cancer
- Brain cancer
Key Benefits
- Mutation Detection: Detects important cancer mutations.
- Enables Personalized Therapy: Helps doctors choose treatments tailored to each patient’s tumor.
- Accelerates Clinical Decision-Making: Provides fast and reliable results for timely treatment choices.
Turn Around Time
- 10 days
Do You Need a Doctor’s Request?
Yes. This test must be ordered by a physician, as the results can impact treatment decisions and require clinical interpretation. Your healthcare provider will determine if the test is appropriate based on your cancer type, stage, and treatment plan.
How it Works?
Step 1: FFPE Tissue Sample Collection
- Preserved tissue sample are collected from biopsies or surgeries.
- Stored in wax blocks, these samples keep DNA intact for testing.
Step 2: DNA Extraction
- We carefully extract the DNA from the sample.
- This DNA is what we need to study your genes.
Step 3: Library Preparation
- The DNA is prepared so it can be read by our sequencing machines.
- We add special tags and focus on the most important parts of your DNA.
Step 4: Next Generation Sequencing
- This is how we ‘’read’’ your DNA using advanced technology.
- It helps us find changes or mutations in your genes.
Step 5: Data Analysis
- Our proprietary software (D-KRYPT) helps us understand what the DNA changes mean.
- The results are derived from trusted medical databases.
Step 6: Personalized Patient Report
- You got a clear, easy-to-read report with important findings.
- Your doctor can use this to guide treatment or next steps.
Oncology Test Panels
Clinical Sequencing
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Regenerative Medicine
Healthcare
Agriculture
Bring Precision Oncology to the Bloodstream
Designed for patients with advanced or inoperable tumors, it supports real-time monitoring of disease evolution and treatment resistance.
A Simple Blood Test for Cancer Insights
If you’re living with advanced or inoperable cancer—or your doctor recommended a liquid biopsy—reach out today to learn how this test can support your treatment journey.
*All information is handled with strict confidentiality.
