Precision Germline Testing for Cancer Predisposition
Screening 69 genes to uncover inherited cancer risks
Hereditary Panel B analyzes inherited 69 genes associated with the most common types of cancer, detecting germline mutations that may increase an individual's risk of developing cancer. This focused panel supports early risk identification, clinical decision-making, and personalized care pathways for individuals and families with a history of cancer.
Who is this Test for?
- You or a family member has had cancer at a young age.
- There is a pattern of cancer in your family.
- You want to know your inherited risk for cancer, even if you’ve never been diagnosed.
- You are looking for a more focused panel that still covers many common hereditary cancer genes.
Variant Types Detected
Single Nucleotide Variants (SNVs)
- SNVs are single base changes between reference and the patient's genome.
Insertions and Deletions (Indels)
- Insertion
- Deletion
- Indels are small changes in DNA where a few bases are either added (insertion) or removed (deletion).
Some Copy Number Variants (CNVs)
- Amplification / Duplication
- Deletion
- Parts of DNA that are copied too many times or missing. This can make cancer genes overactive or silence protective genes.
What it Screens for
- Germline mutations in 69 genes linked to:
- Breast cancer
- Ovarian cancer
- Colorectal cancer
- Prostate cancer
- Endometrial cancer
- Pancreatic cancer
- Renal cancer
- Gastric cancer
- Thyroid cancer
Key Benefits
- Detects Inherited Cancer Risk: Identifies genetic variants that may raise cancer risk.
- Focused Gene Coverage: Includes key genes associated with common hereditary cancers.
- Supports Early Detection: Enables timely screening and preventive care.
- Guides Personalized Health Planning: Helps individuals and families manage long-term cancer risk.
Turn Around Time
- 5-6 weeks
Do You Need a Doctor’s Request?
Yes. A healthcare provider will need to order the test. They will explain the results and help you decide what steps to take if a genetic risk is found.
How it Works?
Step 1: Blood Sample Collection
- A blood draw is taken from the patient.
- The sample contains DNA that can reveal important health insights.
Step 2: DNA Extraction
- We carefully extract the DNA from the sample.
- This DNA is what we need to study your genes.
Step 3: Library Preparation
- The DNA is prepared so it can be read by our sequencing machines.
- We add special tags and focus on the most important parts of your DNA.
Step 4: Next Generation Sequencing
- This is how we ‘’read’’ your DNA using advanced technology.
- It helps us find changes or mutations in your genes.
Step 5: Data Analysis
- Our proprietary software (D-KRYPT) helps us understand what the DNA changes mean.
- The results are derived from trusted medical databases.
Step 6: Personalized Patient Report
- You got a clear, easy-to-read report with important findings.
- Your doctor can use this to guide treatment or next steps.
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*All information is handled with strict confidentiality.
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Early detection saves lives
*All information is handled with strict confidentiality.
