Accurate Reconstruction of Complex Genomes
Turning Fragmented Sequences Into Full Genomic Blueprints
GTx-Genome Assembly™ delivers high-fidelity genome reconstruction by assembling raw sequencing reads into complete, contiguous, and annotated genomes. Whether for microorganisms, plants, or animal samples, this service enables researchers to unlock the full genetic architecture of a species. Ideal for de novo genome projects, comparative genomics, and evolutionary studies, it supports downstream applications such as gene discovery, variant analysis, and functional annotation, ensuring a solid genomic foundation for research and development across health, agriculture, and environmental sciences.
Applications:
- Comparative genomics and evolutionary studies
- Identification and characterization of novel genes and functional elements
- Investigation of genetic variations and disease-causing mutations
- Development of genetic resources for crop improvement and livestock breeding
- Microbial genomics
- Environmental genomics
Key Features:
- Genome Assembly: Reconstructs complete genomes using next- and third-generation sequencing for accurate, contiguous sequences.
- Data Preprocessing: Performs quality control, trims low-quality reads, removes artifacts, and filters contaminants to ensure reliable input.
- De Novo Assembly: Reconstructs genomes without a reference, enabling insights into novel or under-studied organisms.
- Reference-Guided Assembly: Utilizes existing genome sequences as a reference framework to align reads, enabling rapid and accurate detection of diverse variant types, including single-nucleotide variants (SNVs) and copy number variants (CNVs).
- Complete Annotation: Identifies genes, non-coding RNAs, repeats, transposable elements, and structural variants using advanced algorithms and transcriptomic data.
- Functional Annotation: Assigns biological meaning to genomic elements, including gene functions, protein domains, pathways, and regulatory elements.
- Quality Assessment: Evaluates contiguity, coverage, completeness, and accuracy for reliable results.
- Comparative Genomics: Detects conserved regions, gene families, and evolutionary relationships between species.
- Visualization and Interpretation: Provides genome browsers, interactive plots, and detailed reports for easy exploration and actionable insights.
High-Fidelity Genome Assembly for Clinical Research
Contact us to discuss your genome assembly needs.
*All information is handled with strict confidentiality.
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