Clinically Relevant Mutation Detection
Targeted PIK3CA Testing for Personalized Breast & Colon Cancer Care
DNA GTx’s PIK3CA Test detects five clinically significant mutations in the PIK3CA gene, known to play a key role in the development and progression of various cancers, including breast and colorectal cancers. Identifying these somatic mutations can guide treatment selection, particularly the use of PIK3CA-targeted therapies, and support informed, personalized care planning.
Who is this Test for?
- Patients diagnosed with breast, colon, or related cancer
- Those who may benefit from targeted therapies based on PIK3CA mutation status
- Patients needing information to guide personalized treatment plans
What it Screens for
- 5 key mutations in the PIK3CA gene (E542K, E454K, E545Q, H1047R, H1047L)
- Linked to:
- Breast cancer
- Colorectal cancer
- Other solid tumors with PIK3CA pathway activation
Key Benefits
- Actionable Mutation Detection: Identifies PIK3CA mutations that may influence targeted therapy.
- Supports Precision Treatment: Helps guide use of PI3K inhibitors and related therapies.
- Applicable Across Tumor Types: Relevant to multiple cancers with PIK3CA involvement.
- Fast, Focused Results: Delivers targeted insights quickly for timely decision-making.
Turn Around Time
- 3 days
Do You Need a Doctor’s Request?
Yes. A healthcare provider must request this test to ensure proper interpretation and use of the results in your care.
How it Works?
Step 1: FFPE Tissue Sample Collection
- Preserved tissue sample are collected from biopsies or surgeries.
- Stored in wax blocks, these samples keep DNA intact for testing.
Step 2: DNA Extraction
- We carefully extract the DNA from the sample.
- This DNA is what we need to study your genes.
Step 3: PCR Amplification
- Specific regions of DNA are copied millions of times.
- This makes even small mutations easier to detect.
Step 4: Data Analysis
- Our proprietary software (D-KRYPT) helps us understand what the DNA changes mean.
- The results are derived from trusted medical databases.
Step 5: Personalized Patient Report
- You got a clear, easy-to-read report with important findings.
- Your doctor can use this to guide treatment or next steps.
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