Genetic Testing for Inherited Cancer Risk
113 genes analyzed to uncover hereditary cancer susceptibility
DNA GTx’s Hereditary Panel A screens for germline variants across 113 genes known to be associated with the most common types of cancer that could increase cancer risk. This comprehensive panel identifies inherited genetic mutations that may significantly increase the risk of developing cancers such as breast, ovarian, colorectal, endometrial, pancreatic, and others.
Early identification of at-risk individuals enables proactive clinical decisions, including surveillance, preventive interventions, and personalized care planning for patients and their families.
Who is this test for?
- You have a personal or family history of cancer, especially at a young age
- Multiple people in your family have had the same or related cancers
- You’ve had rare or multiple cancers
- You want to know if you carry a hereditary risk for cancer—even if you’re healthy
Variant Types Detected
Single Nucleotide Variants (SNVs)
- SNVs are single base changes between reference and the patient's genome.
Insertions and Deletions (Indels)
- Insertion
- Deletion
- Indels are small changes in DNA where a few bases are either added (insertion) or removed (deletion).
Some Copy Number Variants (CNVs)
- Amplification / Duplication
- Deletion
- Parts of DNA that are copied too many times or missing. This can make cancer genes overactive or silence protective genes.
What it Screens for
- Germline variants in 113 genes linked to:
- Breast cancer
- Ovarian cancer
- Colorectal cancer
- Pancreatic cancer
- Prostate cancer
- Endometrial cancer
- Renal cancer
- Gastric cancer
- Thyroid cancer
Key Benefits
- Identifies Inherited Cancer Risk: Detects genetic variants that may increase lifetime cancer risk.
- Covers Major Cancer Types: Includes genes linked to the most common hereditary cancers.
- Supports Early Detection: Helps guide screening, prevention, and risk-reduction strategies.
- Enables Personalized Care: Provides insights to tailor long-term health management for individuals and families.
Turn Around Time
- 10 days
Do You Need a Doctor’s Request?
Yes. A healthcare provider must order this test. They’ll review your medical and family history, help you understand the results, and guide you on the next steps if a risk is found.
How it Works?
Step 1: Blood Sample Collection
- A blood draw is taken from the patient.
- The sample contains DNA that can reveal important health insights.
Step 2: DNA Extraction
- We carefully extract the DNA from the sample.
- This DNA is what we need to study your genes.
Step 3: Library Preparation
- The DNA is prepared so it can be read by our sequencing machines.
- We add special tags and focus on the most important parts of your DNA.
Step 4: Next Generation Sequencing
- This is how we ‘’read’’ your DNA using advanced technology.
- It helps us find changes or mutations in your genes.
Step 5: Data Analysis
- Our proprietary software (D-KRYPT) helps us understand what the DNA changes mean.
- The results are derived from trusted medical databases.
Step 6: Personalized Patient Report
- You got a clear, easy-to-read report with important findings.
- Your doctor can use this to guide treatment or next steps.
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*All information is handled with strict confidentiality.
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Early detection saves lives
*All information is handled with strict confidentiality.
